Objective To discuss the operative method and its advantages in treating humeral shaft fractures with intramedullary interlocking nail. Methods 16 patients with humeral shaft fractures were treated by antegrade nail insertion with humeral intramedullary interlocking nail.Results 14 patients were followed up. Bone union occurred in 13 cases. Delayed union occurred in 1 case. No nonunion was found. One had injury of radial nerve. The average Neer's score of shoulder was 85±10.Conclusion The treatment of h...