A flow injection chemiluminescence method for the determination of pipernidic acid was studied. It is based on the chemiluminescence reaction of KMnO4-Na2 SO3-pipernidic acid. The main factors which affect the determination were investigated. Under optimum conditions, the linear range for the determination of pipernidic acid was 1.0 × 10~(-7)-8.0 × 10~(-5) g/mL, the determination limit was 3 × 10~(-8)g/mL, the relative standard deviation was 1.6% for 11 measurements to 4.0 ×10~(-6) g/mL pipernidic acid stan...