Objective:To investigate effect of Barley β-glucans on serum cholesterol-lowering in hypercholesterolemic mice.Methods:Mice were fed lipids-rich diets mixed with barley β-glucans.Serum lipids were measured and livers were weighted to calculate liver coefficient.Results:Barley β-glucans effectively lowered cholesterol and low density lipoprotein in plasma,reduced liver coefficient and alleviated pathological changes of fatty liver.Conclusion:Barley β-glucans have hypocholesterolemic effect. The main mechanis...