Objective: To study the effect of satragaloside Ⅳ on the microvascular permeability induced by histamine in pial microvessels. Method: The microvascular permeability was expressed by changes in the transendothelial electrical resistance which was measured with technique using microelectrode impaled into the vascular lumen and based on cable analysis of vessels in rat. Result: The transendothelial electrical resistance of microvessels superfused with artificial cerebrospinal fluid was about 2500 Ω·cm 2, ind...