A new Theory,organic pollutant sequestration inside soil particles, was applied in the research in order to explain the persistence of residual chemicals in remediation sites. Based on this theory, a mathematical model which simulates organic pollutant bioremediation process in soil water microbes system was developed. In the model, diffusion is represented by Fick's second law, reversible sorption desorption by a linear isotherm, irreversible sequestration by a pseudo first order kinetics, and biodegra...