Sarcotesta of Ginkgo biloba L. were subjected to various chemical extractions and successive extracts were monitored for inhibitory activity against the pathogens of fruit trees. Fraction D, composed mainly of anacardic acids, showed remarkable inhibitory activity. Thus, hydroginkgoic acid E was isolated from D. 1 000 times dilution of E showed good activity against Colletotrichum gloeosporioides on apple and grape at the rate of 98.8% and 91.8%, respectively.