To investigate the clinical features and pathological changes of acute nephrotoxicity induced by Aristolochia Manshuriensis Kom (AMK,a Chinese herb)in rats. METHODOLOGY Experimental model of acute renal injury was established in the Sprague Dawley rats with oral administration of decoction of AMK in a dosage of 60g/kg body weight for 5 consecutive days.Serum urea and creatinine levels,urinary activity of N acetyl beta D glucosaminidase(NAG),urina...