Registration between Surgery\|Space and Image\|Space is one of the key factors that affect the accuracy of the brain surgery visualization system.Given two sets of 3\|D corresponding points{ p i } and {p′ i},i=1,2,…,N .Relationship between 3\|D point sets of two spaces fits p′ i=Rp\-i+T, where R is a rotation matrix, T is a translation vector.A four\|point algorithm is presented in this paper for finding the least\|squares solution of R and T ,which is based on the singular value de...