In this experiment,we screened five high laccase -producing strains from many edible fungi strains and studied the ability of AFB,- degradating by laccases.The results show the laccase - producing of the five strains is 413.08 -700.93 U ? L~(-1).790μL crude enzyme can degrade l000ng AFB_1 to 479.97 -226.8ng,and the maximum degradation rate is 77.32%.The unit volume of AFB_1 - degradating of strain is 0.9 - 1.9ng/U.