OBJECTIVE To study the anti-inflammatory effect of Five-taste Hemorrhoids Capsule (FTHC) and its possible mechanism. METHODS The anti-inflammatory effects of FTHC were observed with the models of mouse ear swelling induced by xylene, mouse increasing peritoneal capillary permeability induced by acetic, rat paw swelling induced by carrageen and rat anus swelling induced by croton oil. The anti-inflammatory effects of FTHC were also assessed by checking the changes of MDA content and SOD activity, and examini...