OBJECTIVE:To get a stable dihydroartemisinin liposome with high trapping efficiency by selecting formulation and preparation of dihydroartemisinin liposome.METHODS:The dihydroartemisinin liposomes were prepared by film-ultrasound method.The formulation was optimized by orthogonal design.The trapping efficiency and the stability were determined.RESULTS:The trapping efficiency of the dihydroartemisinin liposome reached 85%,the drug amounted to 30.09% and the particle size of the liposome was 20 nm,The liposom...