OBJECTIVE:To investigate the effect of lipid-bound cysteine mutants of apoA-I on acute gouty arthritis induced by monosodium urate in rats.
METHODS:Twenty-five male Wistar rats(140-160g) were divided randomly into 5 groups:saline control group, model group, soybeanlecithin group, rHDL74 group rHDLwt group, and 5 rats in each group. Except the control group were injected saline, right ankle of the other rats were injected Monosodium urate crystals (MSU) to establish gouty arthritis model. Then all the gr...