L-glutamine is found most abundantly in mammals blood, it is widely used in clinical medicine, nutrition and animal feed. It has broad marketing space and developing prospect.
In this paper, the original strain Corynebacterium acetoacidophilum LG-3 was mutated gradually by UV and DES treatments, a L-glutamine producing strain LG-65 was obtained based on metabolic control principle.Then, the fermentation conditions in shaker flask and 7 L fermentor were studied, and the batch fermentation kinetic in batc...