SPG(Schizophyllan) is a functional polysaccharide fermented by Schizophyllum, with improving immunity, anti-tumor and other biological activities. Schizophyllum has strong decomposition ability of fiber matrix, can make use of agro-processing by-products (corn cob, wheat bran, etc.) to produce SPG to achieve waste to treasure. In this study, we chose high SPG yield strain Schizophyllum, optimized extraction, purification process of SPG, studied irradiation modification of SPG, and functional activit...