Drug micronization ont only reduces the amount of administration, but also improves the bioavailability of actives. Comparing the products that prepared by traditional methods, drug micronized by supercritical CO_2 antisolvent (SAS) has some advantages such as small particle size, homogenous distribution, and low toxic solvent. The technology with wild reaction conditions is conducive to process heat-sensitive materials. In this study, using zein as carrier, resveratrol andβ-carotene as model drug, drug-loa...
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