Hepatocellular carcinoma (HCC) is one of the most frequent malignant tumors and is the second most common cause of cancer death in China. The incidence and mortality of HCC is found increasing year by year. Because of late diagnosis, the prognosis of HCC remains poor. The important measures to improve the survival rate of HCC are early detection, early diagnosis and early treatment; especially the early diagnosis.At present, HCC conventional screening and diagnosis methods include physical examinations, ima...