In this dissertation, breeding of the L-arginine producing strain, optimization of fermentation conditions, as well as metabolic flux analysis were systematically studied based on the fermentation principles of metabolism control. The main research contents and results are as follows:
⑴The L-arginine producer YHR-109 (SGR, Sucg, L-HAR) was obtained from the original strain Corynebacterium glutamicum ZGH-064 by stepwise mutagenic treatments with ultraviolet rays (UV), diethyl sulfate (DES) and ...