The majority of eukaryotic cell protein degradation by the ubiquitin-proteasome pathway (UPP) of the regulation and control. Have reported more than 80% of intracellular protein degradation in the proteasome. Proteasome is a widely distributed in the eukaryotic cell cytoplasm and the nucleus of multi-subunit macromolecular complex, is a function of a variety of protein hydrolysis of macromolecular complexes, which bear the cells in the pan-protein degradation Ub-proteasome pathway plays a catalytic ...