According to the theory of metabolic control fermentation, the paper focuses on the breeding of L-Histidine hyper-producer WH1263, the suitable fermentation condition of shaking flask, the effect of calcium gluconate on L-Histidine fermentation. The main research contents and results are as follows:
The methods of breeding L-Histidine producer from Corynebacterium glutamicum were decided based on the relationship with biosynthesis process of nucleotide and fed-back regulatory mechanism of L-Hist...
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