In this paper ,extracts from opuntia was tested for its antimicrobial activities, including investigation of its antimicrobial spectrum ,MIC value,The feasible solvent with strongest activities was selected after comparing the differences of antimicrobial activities of different extracts from opuntia with different solvents by measuring their antimicrobial activities. The processing conditions of leaching active substances from opuntia were optimized. The sensitivity to universal factors of the extracts was...