Object: The purpose of this study is to examine phagocytic of macrophage; furthermore investigate the mechanism relate to spontaneous rupture of hepatocellular carcinoma (HCC). Method: In this study, we use to look-forward experimentation trial to collect from 9 patients with spontaneous ruptured HCC and 9 patients with non-ruptured HCC. Tumor tissue specimens of patient chooded of post-operation non-haemorrhage putrescence is used to examine: quantificationally investigate to expressions of hepatic macroph...