The neutral protease (NPR) is a protease which suitable pH is 6.0~7.5. It can catalyze the cleavage of peptide bonds in proteins. Since the neutral proteases have many features and advantages in industry such as high speed and wide range of conditions of catalyzed reaction without pollution, they have been extensively used in leather treatment, detergent, food and pharmaceutical industry.
To improve production of the neutral protease and to understand the function of the pro sequence , both the ac...