Object: To explore the effect and mechanism of Motilin in Amygdala on gastric motility. Motilin is a polypeptide composed of 22 amino acid, and secreted by endocrine cells of upper intestine mucosa. Motilin can contract gastric smooth muscle in vitro and regulate gastric contraction of phaseⅢ during the interdigestive state in vivo. It has been proved that motilin-immunoreactive substances and its receptors are wildly distributed in CNS such as cortex, cerebellum, thalamus, hypothalamus, limbic ...