Objective To investigate the effect of VEGF-α on ovarian carcinoma vasculogenic mimicry formation,invasion and migration.Methods The ovarian carcinoma cell lines SKOV-3 and OVCAR-3 were induced by different cytokines.After that the three dimensional culture was used to observe VM formation.Invasion and wound healing assays were performed to judge the invasion and migration ability.Results Three-dimensional culture results demonstrated that both SKOV-3 and OVCAR-3 cells,when stimulated by VEGF-α,formed typic...