[Objective] The aim was to construct a method for the determination of histamine in fishery products by HPLC-UV.[Method] Histamine in the test sample was extracted with perchloric acid,and then derived by dansyl chloride,and nextly determined by high performance liquid chromatograph with UV detector,at last quantified by an external standard mode.[Result] The histamine showed a good linear relationship within the range of 0.5-20 μg/ml with the correlation coefficient r >0.999.The average recoveries ranged f...