[Objective] The aim was to study the antibacterial effect of Fructus Ligustri Lucidi.[Method] By using test tubes serial dilution method,the antibacterial effect of different dilution degrees of Fructus Ligustri Lucidi on Staphylococcus aureus,Escherichia coli and Bacillus subtilis was determined.[Result] The MIC and MBC of Fructus Ligustri Lucidi decoction to Staphylococcus aureus and E.coli were 31 mg/ml and 62 mg/ml respectively,while that of the decoction to Bacillus subtilis were 4 mg/ml and 8 mg/ml.[C...