This paper introduces the architecture of the Portable Electromedical Ultrasonic Equipment (PEUE) and analyzes the feasibility of applying SQLite3 database in such instrument.Based on the research of PEUE project,this paper presents a method that using SQLite3 as database middleware in PEUE to replace the way that using files to manage and storage all medical records.The method improves the efficiency of records index,searching and accessing in PEUE,especially when using FLASH chip as the storage media.