Based on the ANSYS Parametric Design Language(APDL),build the models by nodes,which can show the three-dimensional welding temperature field and stress field of the welding process of JFE-HITEN 780S high-strength steel with CO2 gas shielded arc welding by the numerical simulation.With the models,this paper has simula-ted the actual welding process of thick plate of JFE-HITEN780S high-strength steel,and analyzed the causes and pre-vention measures of the hot cracking during welding.