Aim To explore the role of modified simiao powder and its effective fractions in reducing the uric acid.Method The rat model of hyperuricemia was replicated by hypoxanthine and uricase inhibitor.Rats were administrated modified simiao powder and its effective fractions and the uric acid concentration of serum,urine,joint cavity and ken homogenate was determined.Results Modified simiao powder can decrease the uric acid concentration in serum,urine,and joint cavity(P<0.01,P<0.05,P<0.01,respectively).Effective...