[Objective] The research aimed to optimize the ultrasonic assisted extraction technology for water-soluble active material from E.prolifera.[Method] With fresh E.prolifera from the sea area of Qingdao as tested materials,the water-soluble activity material from E.prolifera was extracted by ultrasonic assisted extraction technology.The effects of extraction time,extraction temperature and ultrasonic power on the extraction yield were investigated through single factor experiments.The extraction technology wa...