[Objective] The study was to provide the scientific basis for rational utilization of Chinese medicine produced in Guizhou.[Method] With 12 kinds of Chinese medicine produced in Guizhou(water dropwort,purslaue,polygonum capitatum atractylodes,tuberfleeceflower,gentian,dendrobium and dwarf lityturf etc) as the materials,the contents of 5 kinds of heavy metal and 5 kinds of metal element that beneficial to human in them was determined.[Result] In 12 kinds of Chinese medicine,the content ranges of As,Hg,Cd,Cu ...