Single-factor and orthogonal array methods were adopted to optimize the ultrasonic extraction of cochineal dye.The optimal conditions for the improved extraction of cochineal dye were determined as follows:ratio of material to solvent 1:6,ultrasonic power 1400 W,ultrasonic treatment time 12 min,pulse on time 10 min,pulse off time 4 min,and extraction number 5.Under these conditions,the yield of cochineal dye was 42.08%.