Summarized the application research status of fruit, flower and stem of Hylocereus undatus.Emphatically introduced the nutritional components,health care value of fruit,flower and stem of Hylocereus undatus,and the processing technologies on fruit juice,fruit wine,preserved fruit,fruit vinegar,acidophilus milk,fruit jam,can,ice cream,health drink and dry flower of Hylocereus undatus,and viewed the development and application prospect of Hylocereus undatus.