Primary liver cancer remains one of the most lethal malignancies worldwide. Due to differences in prevalence of etiological factors the incidence of primary liver can-cer varies among the world, with a peak in East-Asia. As this disease is still lethal in most of the cases, research has to be done to improve our understanding of the disease, offering insights for possible treatment options. For this purpose, animal models are widely used, especially mouse models. In this review, we describe the different ty...
【英文摘要】
Primary liver cancer remains one of the most lethal ma-lignancies worldwide. Due to differences in prevalence of etiological factors the incidence of primary liver can-cer varies among the world, with a peak in East-Asia. As this disease is still lethal in most of the cases, research has to be done to improve our understanding of the disease, offering insights for possible treatment op-tions. For this purpose, animal models are widely used, especially mouse models. In this review, we describe the different ...