The beneficial effect of γ-Aminobutyric acide(GABA) considered in the present review night include the inhibition of blood pressure,improve condition of brain and increase the sperm acrosin activity,expatiation the composed and intensify of GABA,especially the manner and mechanism of Lactic acid bacteria catalyse L-glutamic acid into GABA. Finally,several ready-to-use methods for the determination of GABA were given.