OBJECTIVE To design the prescription of a nasal gel and control its quality.METHODS Carbomer-940 and glycerol was used as the main materials to prepare the gel,triethanolamine was used to regulate pH,the content was determined by UV spectrophotometer and polarmetric analysis.RESULTS The quality of gel was stable,the content of the gel was accurate.The average recovery of ofloxacin was 101.1%,RSD=0.92%(n=6);The average recovery of Ephedrine was 100.74%,RSD=1.96%(n=6).CONCLUSION The preparation and quality co...