dynamic progress of depressurization exploitation of Huai-Nan mining area is researched by numerical simulation instrument.Differential pressure and distortion of different overburden structure layered stratum is simulated by RFPA2D.The Depressurization effect of different Key layer stratum is analyzed by the numerical simulated result.Key layer possess visibility position effect and some significant conclusion,which adapt to different overburden structure layered stratum,is testified.