BACKGROUND & AIM:To investigate the role of MT-3 in transitional cell carcinomas of bladder and the possible relation with MDR-1.MATERIALS AND METHODS:Using RT-PCR technique,the expressions of MT-3 and MDR-1 mRNA in 11 specimens from normal bladder mucosa and 23 specimens from bladder transitional cell cancer(BTCC)were measured.RESULTS:MT-3 and MDR-1-positive expression rates were found in 0 and 9.1% in normal bladder mucosa,respectively.But they were 78.3% and 56.5% in 23 BTCC specimens,respectively.The po...
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