The research progress on the molecular structure,physiochemical properties and physiological functions of momordicosides are reviewed. Some problems that we should pay attention to in the study on momordicosides are also mentioned. The chemical research on momordicosides shows that momordicosides is a kind of compounds with cucurbitanes-type tetracyclic triterpenoids. Modern medical studies showed that momordicosides had many physiological functions such as reducing blood sugar,enhancing immunity,anti-oxidi...