Magnetic resonance spectroscopy based on the principles of magnetic resonance, the chemi-cal shift, and spin coupling is a technique that allows examination of the metabolites and biochemical nature in vivo without the need for invasive procedures. Non-invasive detection of metabolite concentration using MR spectroscopy can provide valuable information in diagnosis and treatment of diseases. In localized brain MR spectroscopy, the measurement results of brain metabolites had often been expressed as ratios r...