Objective To examine the distribution of GABA immunoreactive neurons in the lumbar spinal cord of young adult and aged cats, and to explore the change and significamce of the distribution of GABAergic neuronsin the spinal cord related to age. Methods Immunohistochemical method was applied. Results GABA immunoreactive cells and fibers were widely distributed in the gray matter and appeared in all Rexed laminae of the lumbar spinal cord, with stronger immunoreaction in the dorsal horn than in the ventral horn...