The application, downstream products synthesis and development of Nicotinic Acid (3-NC) are reviewed. 3-NC has biological and chemical activities as intermediates of fine chemical and medicine, which is widely used to derive a series of products with high value. This paper mainly introduces Nicotinic Acid, Chromium Nicotinate, Inositol Hexanicotinate, Ve Nicotinate and 2-Chloro-3-Pyridinecarboxylic acid.