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Application of Proteomics in the Study of Tumor Metastasis  
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【英文篇名】 Application of Proteomics in the Study of Tumor Metastasis
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【英文作者】 Zhen Cai1; Jen-Fu Chiu2; and Qing-Yu He2 *; 3; 4 1Department of Surgery; Open Laboratory of Chemical Biology of the Institute of Molecular Technology for 2 Drug Discovery and Synthesis; Institute of Molecular Biology; Department of Chemistry; The University of 3 4 Hong Kong; Hong Kong; China.;
【文献出处】 Genomics Proteomics & Bioinformatics , 基因组蛋白质组与生物信息学报(英文版), 编辑部邮箱 2004年 03期  
期刊荣誉:ASPT来源刊  CJFD收录刊
【英文关键词】 proteomics; metastasis; tumor mechanism; protein identi?cation; MALDI-TOF; SELDI-ProteinChip;
【英文摘要】 Tumor metastasis is the dominant cause of death in cancer patients. However, the molecular and cellular mechanisms underlying tumor metastasis are still elusive. The identi?cation of protein molecules with their expressions correlated to the metastatic process would help to understand the metastatic mechanisms and thus facilitate the development of strategies for the therapeutic interventions and clini- cal management of cancer. Proteomics is a systematic research approach aiming to provide the global chara...
【基金】 This work was partially supported by Hong Kong Re-search Grants Council Grants HKU 7227/02M (toQ.Y.H.), HKU 7218/02M and HKU 7395/03M (toJ.F.C.), the Department of Chemistry, and the Areasof Excellence scheme of Hong Kong University GrantsCommittee.
【更新日期】 2005-08-19
【分类号】 R730.2
【正文快照】 Tumor MetastasisAlthough diagnostic technology and therapeutictreatment have made vast progress during the lastdecades, cancer mortality remains high, accountingfor approximately 25% of the deaths in the developedworld (1). Metastasis is by far the leadin

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医药、卫生
  肿瘤学
   一般性问题
    肿瘤病理学、病因学
  
 
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