Multimodality medical image registration plays an important role in clinical diagnosis and therapy planning. A novel automatic registration method based on contour feature points and particle swarm optimization (PSO) is presented. Firstly, the images are pretreated by using rust and expansion operations, and the edges of images are detected by using region growth method; then an algorithm called subtractive is used to educe the contour feature points; the minimum value of the root-mean-square for the two fe...