An approach of a CCD signal transmission through long-wire is presented. By using the characteristic of LVDS (low voltage differential signal), first, the channel link standard signal of CCD camera is transformed into TTL levels, the date of TTL levels filtered and buffered by FPGA(field programmable gate array) are transformed into LVDS, then LVDS are transmitted through long-wire. This method can meet the need of real-time transmission and avoid the interference of random signals.