BACKGROUND & AIM: Although Duzhong was listed on the function food roll, there was lack of data of systematic toxic/safety evaluation experiments. MATERIAL AND METHODS: Safety evaluation experiment was done using acute toxicity experiment, cell toxicity experiment and genetic toxicity experiment . RESULTS: CHL and CHO were 109.38 mg/ml; it was negative in toxicity. CONCLUSION: It was found that Du zhong was a non-toxic substance and was negative in genetic toxicity, although it had some toxic effect on the ...