Objective To study the effect of venlafaxine plus cognitive behavior therapy in treatment of panic disorder. Methods 37 outpatients who met CCMD-2-R for panic disorder were assigned to therapeutic group(n = 19)and control group(n= 18)for 6 months. Therapeutic group were given venlafaxine (50-150mg/d)in addition to congnitive behavior therapy,and control group were given venlafaxine (50-150mg/ d)only. The clinical effect was assessed with HAMA , CGI-SI at the end of 1 month, 3 months and 6 months. Results Th...