Objective: The pharmacokinetic parameters in 10 healthy volunteers and the in vitro antibacterial activity of cefprozil were evaluated. Methods: 10 healthy volunteers received a single dose of 500 mg cefprozil tablet. The serum concentrations of cefprozil were measured by bioassay. The MIC of cefprozil against common bacteria were measured by agar dilution method. Results: The main pharmacokinetic parameters were as follows: c max (9.36±1.18) mg/L, t max (1.23±0.45) h, t 1/2β (...
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