Preliminary Studies on Base Substitutions and Repair of DNA Mismatch Damage Stimulated by Low Energy N~+ Ion Beam Implantation in Escherichia coli 推荐 CAJ下载
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【英文篇名】
Preliminary Studies on Base Substitutions and Repair of DNA Mismatch Damage Stimulated by Low EnergyN~+ Ion Beam Implantation in Escherichia coli
<正> Ever since the low energy N+ ion beam has been accepted that the mutation effects of ionizing radiation are attributed mainly to direct or indirect damage to DNA. Evidences based on naked DNA irradiation in support of a mutation spectrum appears to be consistent, but direct proof of such results in vivo are limited. Using mutS, dam and/or dcm defective Eschericha coli imitator strains, an preliminary experimental system on induction of in vivo mutation spectra of low energy N+ ion beam has been establis...
【英文摘要】
Ever since the low energy N+ ion beam has been accepted that the mutation effects of ionizing radiation are attributed mainly to direct or indirect damage to DNA. Evidences based on naked DNA irradiation in support of a mutation spectrum appears to be consistent, but direct proof of such results in vivo are limited. Using mutS, dam and/or dcm defective Eschericha coli imitator strains, an preliminary experimental system on induction of in vivo mutation spectra of low energy N+ ion beam has been established ...
【基金】
The project supported by the National Nature Science Foundation of China (No. 19890300)
【分类号】
Q691
【正文快照】
1 IntroductionThe low energy N+ion beam has been character—ized as an e伍cient physical mutagen in pIant andmicrobe breeding[¨,cell bystander effect and cy—toplasm irradiation effect[2,引. But the mechanismXIE Chuall.xiao e七a1.:DNA Mismatch Damage Sti
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