<正> AIM:To investigate the effects of IH764-3 on HSC apoptosis,and the expression of caspase-3 protein in HSC apoptoticprocess.METHODS:HSCs were cultured in medium with differentIH764-3 doses(10μg·mL~(-1),20μg·mL~(-1),30μg·mL~(-1),40μg·mL~(-1))and without IH764-3,and HSC proliferation wasquantitatively measured by ~3H-thymidine incorporation.Themorphological changes of HSCs were observed withtransmission electron microscope after exposure to the doseof 40μg·mL~(-1)of IH764-3 for 48 hr.The apoptosis rates we...
【英文摘要】
AIM:To investigate the effects of IH764-3 on HSC apoptosis, and the expression of caspase-3 protein in HSC apoptotic process. METHODS:HSCs were cultured in medium with different IH764-3 doses(10μg·mL~(-1),20μg·mL~(-1),30μg·mL~(-1),40μg· mL~(-1))and without IH764-3,and HSC proliferation was quantitatively measured by ~3H-thymidine incorporation.The morphological changes of HSCs were observed with transmission electron microscope after exposure to the dose of 40μg·mL~(-1)of IH764-3 for 48 hr.The apoptosis rat...
【基金】
Fund of the Scientific and Technical Department of Hebei Province,No.01276134
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